Mandell AI, Stentz F & Kitabchi AE
Dipivalyl epinephrine: a new pro-drug in the treatment of glaucoma.>
Ophthalmology, 85(3): 268-275, 1978
ISSN: 0161-6420 Ophthalmology (PubMed)
Abstract
The dansyl chloride technique in conjunction with thin layer chromatography and autoradiography has shown that dipivalyl epinephrine is a pro-drug in the human eye. Dipivalyl epinephrine appears to be a more effective epinephrine compound, in that it penetrates the cornea approximately 17 times greater than epinephrine.